IL-6 anticorps (Biotin)

N° du produit ABIN6963872

Cet anticorps Rat Monoclonal détecte spécifiquement IL-6 dans ELISA et ELISpot. Il présente une réactivité envers Humain et Non-Human Primate et a été mentionné dans 4+ publications.

Aperçu rapide pour IL-6 anticorps (Biotin) (ABIN6963872)

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivité: Humain, Non-Human Primate

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-6 est conjugé à/à la Biotin

Application: ELISA, ELISpot

Clone: 39C3

Détail du produit anti-IL-6 anticorps (Biotin)

Specificité: Native and recombinant IL-6

Réactivité croisée (Details): The monoclonal antibody cross-reacts with IL-6 from non-human primates.

Attributs du produit: This monoclonal antibody enables specific detection of human IL-6 in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

Purification: Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human IL-6

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

ABIN6963872 and ABIN7448315 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAb ABIN6963871, ABIN7448314 and ABIN6964024 .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Date de péremption: 18 months

Références pour anticorps anti-IL-6 (Biotin) (ABIN6963872)

Järver, Dondalska, Poux, Sandberg, Bergenstråhle, Sköld, Dereuddre-Bosquet, Martinon, Pålsson, Zaghloul, Brodin, Sander, Lennox, Behlke, El-Andaloussi, Lehtiö, Lundeberg, LeGrand, Spetz: "Single-Stranded Nucleic Acids Regulate TLR3/4/7 Activation through Interference with Clathrin-Mediated Endocytosis." dans: Scientific reports, Vol. 8, Issue 1, pp. 15841, (2019) (PubMed).

Zhenjiang, Rao, Luo, Valentini, von Landenberg, Meng, Sinclair, Hoffmann, Karbach, Altmannsberger, Jäger, Peredo, Dodoo, Maeurer: "Cytokine Networks and Survivin Peptide-Specific Cellular Immune Responses Predict Improved Survival in Patients With Glioblastoma Multiforme." dans: EBioMedicine, Vol. 33, pp. 49-56, (2018) (PubMed).

Phuah, Wong, Gideon, Maiello, Coleman, Hendricks, Ruden, Cirrincione, Chan, Lin, Flynn: "Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques." dans: Infection and immunity, Vol. 84, Issue 5, pp. 1301-1311, (2017) (PubMed).

Min, Wang, Yuan, Kuang, Zhao: "Effects of repeated tuberculin skin testings on immune responses in experimental monkeys." dans: Journal of animal science and technology, Vol. 56, pp. 32, (2015) (PubMed).

Détails sur IL-6

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Autre désignation: IL6

ID gène: 3569

Pathways: Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome